State-of-the-art Mobility Testing for Inherited Retinal Diseases
A test using Virtual Reality (VR)
- Calibrated against physical test
- Precise control over experimental parameters
- Quick and safe assessments
- Consistent results across various centers
A validated and sensitive outcome
- A realistic task inspired by daily life
- Detailed measurement of functional vision
- Captures patient challenges
- Sensitive to change in visual function
- Minimizes learning effects
A VR solution for global use
- Two-day setup for installation, validation, and training
- Automated performance assessment with a quality check reading center
- User-friendly for site personnel
- Interface available in multiple languages
A new mobility performance measurement tool designed to measure disease progression and therapeutic benefit in inherited retinal diseases
A test using Virtual Reality
We designed and validated MOST in both physical and virtual reality settings. VR offers fine control over experimental parameters such as luminance and contrast for tailored assessments, ensures fast and safe evaluations, suitable for various conditions, and guarantees reproducibility across different centers
*Authié et al., 2024, AJO
A validated and sensitive outcome
MOST-VR offers a valid and sensitive measurement of functional vision through a mobility task that reflects daily activities, accurately capturing the mobility challenges patients encounter. It provides a mobility performance score that is responsive to changes in visual function, while effectively reducing learning effects.
A VR solution for global use
MOST-VR is a globally-ready VR solution that streamlines setup, validation, and training into just two days. Its automated assessment and quality control are user-friendly for site staff, with an interface in English, French, and Italian, facilitating widespread adoption.
MOST-VR Services
MOST-VR INSTALLATION
All required material are shipped to the site. Once at the site, Streetlab technicians mount the VR system (motion capture for the room) and a table with a computer controlling the VR headset, in one-day.
SITE TRAINING & CERTIFICATION
Streetlab technicians lead a 1-day practicum explaining how to operate the mobility test and how to process patients. Once technicians at the site demonstrate proficiency, they are authorized to perform the test.
AUTOMATIC SCORING & READING CENTER
The test is user-friendly for site personnel. The performance score is computed automatically, and checked by our reading center at Streetlab.
Installed Sites
Scientific validation
Journals
Authié, C. N., Poujade, M., Talebi, A., Defer, A., Zenouda, A., Coen, C., Mohand-Said, S., Chaumet-Riffaud, P., Audo, I., & Sahel, J.-A. (2024). Development and validation of a novel mobility test for rod-cone dystrophies, from reality to virtual reality. American Journal of Ophthalmology, S0002939423002799. https://doi.org/10.1016/j.ajo.2023.06.028
Sahel, J.-A., Grieve, K., Pagot, C., Authié, C., Mohand-Said, S., Paques, M., Audo, I., Becker, K., Chaumet-Riffaud, A.-E., Azoulay, L., Gutman, E., Léveillard, T., Zeitz, C., Picaud, S., Dalkara, D., & Marazova, K. (2021). Assessing Photoreceptor Status in Retinal Dystrophies: From High-Resolution Imaging to Functional Vision. American Journal of Ophthalmology, 230, 12–47. https://doi.org/10.1016/j.ajo.2021.04.013
Book section
Chung, D., Authié, C., & Blouin, L. (2023). Mobility Testing and Other Performance-Based Assessments of Functional Vision in Patients with Inherited Retinal Disease. Cold Spring Harbor Perspectives in Medicine, a041299. https://doi.org/10.1101/cshperspect.a041299
Conferences
Pagot, C., Authié, C., Poujade, M., Becker, K., Defer, A., Talebi, A., Ajasse, S., Coen, C., Mohand-Said, S., Chaumet-Riffaud, P., Sahel, J.A., Audo, I. (2023). Validation de deux tests de mobilité en situation réelle et virtuelle pour des sujets atteints de rétinopathie pigmentaire à différents stades de la maladie. Congrès d’Automne de la SGOF, 13 et 14 octobre 2023, Venise, Italy
Authié, C. N., Audo, I. (2023). Validation of PRO and PerfOs for inherited retinal diseases. Journées de la recherche clinique, 13-18 Oct 2023, Paris France
Authié, C. (2023). Validation de nouveaux tests comportementaux d’exploration en recherche clinique. Jan. 26-27, (2023). Réunion d’hiver du CNOF, Bruxelles, Belgium.
Poujade, M., Blouin, L., Authié, C. N., Chung, D., Le Meur, A., Neufer, K., Celle, A., Sahel, J. A., & Audo, I. (2023). Mobility and Postural Testing in Patients with Rod-Cone Dystrophy Enrolled in the Prospective Natural History Study PHENOROD2. Invest. Ophthalmol. Vis. Sci., 64(8):4644. https://iovs.arvojournals.org/article.aspx?articleid=2789009
Authié, C. N., Poujade, M., Talebi, A., Defer, A., Zenouda, A., Coen, C., Zhang, Y., Sahel, J.-A., Saddek, M.-S., Chaumet-Riffaud, P., & Audo, I. (2022). Development and validation of a mobility test for Inherited Retinal Disease in real and virtual conditions – preliminary results. Invest. Ophthalmol. Vis. Sci., 63. https://iovs.arvojournals.org/article.aspx?articleid=2779458